A survey of approaches for direct parametric image reconstruction in emission tomography.
نویسندگان
چکیده
The quantitative data obtained by emission tomography are decoded using a number of techniques and methods in sequence to provide physiological information. Conventionally, the data are reconstructed to produce a series of static images. Then, pharmacokinetic modeling techniques are applied, and kinetic parameters that have physiological or functional significance are derived. Although it is possible to optimize each estimation step in this process, many simplifying assumptions have to be introduced to make the methods that are used practicable. Published research has shown that if the kinetic parameters are estimated directly from the measured data, the parametric images will have higher quality and lower mean-squared error than if this was done indirectly. This review highlights some aspects of the methods that have been proposed for such direct estimation of pharmacokinetic information from raw emission data.
منابع مشابه
Direct Estimation of Kinetic Parametric Images for Dynamic PET
Dynamic positron emission tomography (PET) can monitor spatiotemporal distribution of radiotracer in vivo. The spatiotemporal information can be used to estimate parametric images of radiotracer kinetics that are of physiological and biochemical interests. Direct estimation of parametric images from raw projection data allows accurate noise modeling and has been shown to offer better image qual...
متن کاملUtilization of an optimum low-pass filter during filtered back-projection in the reconstruction of single photon emission computed tomography images of small structures
Introduction:Low-pass filters eliminate noise, and accordingly improve the quality of filtered back-projection (FBP) in the reconstruction of single photon emission computed tomography (SPECT) images. This study aimed at selection of an optimum low-pass filter for FBP reconstruction of SPECT images of small structures. Material and Methods:Sp...
متن کاملImage Optimization in Single Photon Emission Computed Tomography by Hardware Modifications with Monte Carlo Simulation
Introduction: In Single Photon Emission Computed Tomography (SPECT), the projection data used for image reconstruction are distorted by several factors, including attenuation and scattering of gamma rays, collimator structure, data acquisition method, organ motion, and washout of radiopharmaceuticals. All these make reconstruction of a quantitative SPECT image very difficult. Simulation of a SP...
متن کاملPerformance Evaluation of FBP Reconstruction in SPECT Imaging
Introduction: The purpose of this study is to define the optimal parameters for the tomographic reconstruction procedure in a routine single photon emission tomography. The Hoffman brain phantom is modified to evaluate the reconstruction method. The phantom was imaged in a 3 and 2-dimensional conformation and the results were compared. Materials and Methods: The 2D phant...
متن کاملComparison of Count Normalization Methods for Statistical Parametric Mapping Analysis Using a Digital Brain Phantom Obtained from Fluorodeoxyglucose-positron Emission Tomography
Objective(s): Alternative normalization methods were proposed to solve the biased information of SPM in the study of neurodegenerative disease. The objective of this study was to determine the most suitable count normalization method for SPM analysis of a neurodegenerative disease based on the results of different count normalization methods applied on a prepared digital phantom similar to one ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Medical physics
دوره 35 9 شماره
صفحات -
تاریخ انتشار 2008